A Design for the 178-MHz WXGA 30-fps Optical Flow Processor Based on the HOE Algorithm

We propose an optical flow processor, which allows real-Time processing of WXGA 30-fps at 178.3 MHz. By introducing the SOR method and a pipeline operation for the Gauss-Seidel method to the iterative flow calculation, computational complexity can be reduced to 14.5% when compared to the previous HOE processor. We decreased the area of the embedded memory by using the image division method, applying line memory, and optimizing the computation word length. The core size of the designed processor is 16.82 mm2 in 90 nm process technology, which is approximately 5% of the previous HOE processor. The processor can operate completely in parallel, which ensures high-resolution scalability. © 2015 IEEE.18th IEEE International Symposium on Design and Diagnostics of Electronic Circuits and Systems, DDECS 2015; Belgrade; Serbia; 22 April 2015 through 24 April 2015; Category numberE5519; Code 11688

A Design for the 178-MHz WXGA 30-fps Optical Flow Processor Based on the HOE Algorithm

We propose an optical flow processor, which allows real-Time processing of WXGA 30-fps at 178.3 MHz. By introducing the SOR method and a pipeline operation for the Gauss-Seidel method to the iterative flow calculation, computational complexity can be reduced to 14.5% when compared to the previous HOE processor. We decreased the area of the embedded memory by using the image division method, applying line memory, and optimizing the computation word length. The core size of the designed processor is 16.82 mm2 in 90 nm process technology, which is approximately 5% of the previous HOE processor. The processor can operate completely in parallel, which ensures high-resolution scalability. © 2015 IEEE. 18th IEEE International Symposium on Design and Diagnostics of Electronic Circuits and Systems, DDECS 2015; Belgrade; Serbia; 22 April 2015 through 24 April 2015; Category numberE5519; Code 11688

Establishment of a novel collagenase perfusion method to isolate rat pancreatic stellate cells and investigation of their gene expression of TGF-beta1, type I collagen, and CTGF in primary culture or freshly isolated cells.

In studies of the pathogenesis of pancreatic fibrosis, pancreatic stellate cells (PSCs) have recently gained attention. In the present study, we established a new collagenase perfusion method through thoracic aorta cannulation to isolate PSCs, and we studied gene expression of TGF-beta1, type I collagen, and connective tissue growth factor using primary cultured PSCs. Our method facilitated PSC isolation, and by our new method, 4.3 +/- 1.2 x 10(6) PSCs were obtained from a rat. In comparing the expression of these genes with that of hepatic stellate cells (HSCs), we observed a similar pattern, although PSCs expressed type I collagen gene earlier than did HSCs. These results suggest that PSCs may play an important role in fibrosis of the pancreas, as HSCs do in liver fibrosis; in addition, PSCs may exist in a preactivated state or may be more easily activated than are HSCs. We also isolated the PSCs from a WBN/Kob rat, the spontaneous pancreatitis rat, and compared the gene expression with that from a normal rat

膵癌における癌遺伝子および癌抑制遺伝子

Recent advances in molecular biology have revealed that a number of oncogenes (K-ras, erbB-2, and Met) and tumor suppressor genes (p53, p16, APC, and DCC) contribute to the development of pancreatic cancer. This paper reviewed the present knowledge of oncogenes and tumor suppressor genes relevant to pancreatic cancer. Further studies on molecular alterations in pancreatic cancer may lead to a better understanding of tumor biology, offering a possibility of development of new diagnostic and therapeutic approaches in the future.膵癌の予後は惨憺たるものである｡一方で,最近の分子生物学の分野での研究の進歩により,遺伝子レベルでの異常が膵癌では数多く存在することも明らかになってきた｡膵癌の予後を改善するために,発展が期待される膵癌における遺伝子診断や遺伝子治療に向けて現在までの膵癌で明らかになった癌遺伝子(k-ras,erbB-2,Met),癌抑制遺伝子(p53,p16,APC,DDC)について,概説した

A Field Programmable Sequencer and Memory with Middle Grained Programmability Optimized for MCU Peripherals

A Field Programmable Sequencer and Memory (FPSM), which is a programmable unit exclusively optimized for peripherals on a micro controller unit, is proposed. The FPSM functions as not only the peripherals but also the standard built-in memory. The FPSM provides easier programmability with a smaller area overhead, especially when compared with the FPGA. The FPSM is implemented on the FPGA and the programmability and performance for basic peripherals such as the 8 bit counter and 8 bit accuracy Pulse Width Modulation are emulated on the FPGA. Furthermore, the FPSM core with a 4K bit SRAM is fabricated in 0.18µm 5 metal CMOS process technology. The FPSM is an half the area of FPGA, its power consumption is less than one-fifth.Embargo Period 6 month

Delayed Brain Edema and Swelling following Craniectomy for Evacuation of an Epidural Abscess that Improved by Cranioplasty: Case Report

We report a unique case of delayed brain swelling following craniectomy that improved rapidly after cranioplasty, and discuss the potential mechanism underlying this delayed and reversible brain swelling. A 22-year-old woman developed surgical site infection after removal of a convexity meningioma. Magnetic resonance imaging revealed an epidural abscess around the surgical site. Subsequently, the abscess was evacuated, and the bone flap was removed. Later, brain edema around the skull defect emerged and progressed gradually, despite resolution of the infection. The edematous brain developed focal swelling outward through the bone defect without ventricle dilatation. Because we suspected that the edema and swelling were caused by the state of the bone defect, we performed a cranioplasty 10 weeks after the bone flap removal, and brain edema improved rapidly. We hypothesized that the brain edema was initially caused by surgical stress and inflammation, followed by compression of cortical veins between the dural edge and brain tissue, leading to disruption of venous return and exacerbation of brain edema. When delayed focal brain edema and external swelling progress gradually after bone flap removal, after excluding other pathological conditions, cranioplasty should be considered to improve cortical venous congestion caused by postsurgical adhesion

Prediction of Boron Concentrations in Blood from Patients on Boron Neutron Capture Therapy

Background: In boron neutron capture therapy, blood boron concentration is the key factor to calculate radiation dose, however, blood sampling is difficult during neutron irradiation. Materials and Methods: The prediction of blood boron concentrations for BNCT treatment planning has been prospectively investigated using patient data obtained at first craniotomy after the infusion of a low dose of sodium undecahydroclosododecaborate. Results: The boron biodistribution data showed a biexponential pharmacokinetic profile. If the final boron concentration at 6 or 9 hours after the end of the infusion is within the 95% confidence interval of the prediction, direct prediction from biexponential fit will reduce the error of blood boron concentrations during irradiation to around 6%. Conclusion: Actual boron concentrations during BNCT were reasonably and accurately predictable from the test data

Malignant Lymphoma in the Parasellar Region

The entity of pituitary (sellar or parasellar) lymphoma includes primary pituitary lymphoma (PPL) and secondary pituitary lymphoma (SPL). The latter has an involvement of systemic lymphoma. Both of these lymphomas are extremely rare. We describe a patient with SPL showing a good prognosis. A 78-year-old woman presented with diplopia, left ptosis, and back pain. Magnetic resonance (MR) imaging revealed a parasellar mass lesion extending to the upper clivus and another mass lesion with compression fracture of the Th3 vertebral body. Transsphenoidal exploration was performed, and it showed diffuse large B-cell lymphoma. Based on the positive tumor cells in the following bone marrow aspiration and hepatosplenomegaly in computed tomography (CT) findings, this patient was diagnosed as having a pituitary involvement of systemic lymphoma. After chemotherapy, she achieved complete remission for 4 years. The entity of pituitary lymphoma is extremely rare. Nineteen cases of PPL and 16 cases of SPL have been reported. Generally, clinical and radiological diagnosis was difficult because there are no specific findings. Therefore, biopsy was necessary in all of the cases. T2 hypointensity of a lesion in MR imaging in addition to an elevated serum level of soluble interleukin-2 receptor (sIL-2R) in a patient with a sellar lesion can be useful clues for the differential diagnosis of this rare disease